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Image Search Results
Journal: International Journal of Oncology
Article Title: Increased interleukin-17A levels promote rituximab resistance by suppressing p53 expression and predict an unfavorable prognosis in patients with diffuse large B cell lymphoma
doi: 10.3892/ijo.2018.4299
Figure Lengend Snippet: Rituximab upregulates the level of IL-17A and the percentages of Th17 cells and IL-17 + Foxp3 + Treg cells in vitro . Co-cultures under 7 different conditions as described in the Materials and methods were defined as groups a-g. (A and B) Representative FACS plots of Th17 cells and IL-17 + Foxp3 + Treg cells in the co-cultures from each group. The numbers displayed are the percentages of Th17 cells and IL-17 + Foxp3 + Treg cells. (C-E) Graphs of the Th17 cells andIL-17 + Foxp3 + Treg cell percentages, and IL-17A in each group. The plots and bars in (B-E) are labeled in the same manner (groups a-g) as in (A); groups a-g in (B-E) represent the same groups as those in (A). Error bars represent standard deviation (SD). Significance was determined using single-factor analysis of variance (one-way ANOVA) with Student-Newman-Keuls/Dunnett's T3 test (3 groups). * P<0.05 and ** P<0.01. The data are from 1 of 3 independent experiments. SU, SU-DHL-4 cells; R, rituximab; aIL-6, neutralizing antibody to IL-6.
Article Snippet: Human recombinant IL-6 (Cat. no. 206-IL) and IL-17A (Cat. no. 7955-IL), and human neutralizing antibodies to
Techniques: In Vitro, Labeling, Standard Deviation